Publications

Matabaro, E.; Song, H.; Sondregger, L.; Gherlone, F.; Giltrap, A. M.; Liver, S.; Gossert, A. D.; Künzler, M.; Naimsith, J. H. Macrocyclization of backbone N-methylated peptides by a prolyl oligopeptidase with a distinctive substrate recognition mechanism, Chemical Science, 2025, Advance Article 

Demyanenko, Y.; Sui, X.; Giltrap, A. M.; Davis, B. G.; Kuster, B. and Mohammed, S.; Addressing NHS Chemistry: Efficient Quenching of Excess TMT Reagent and Reversing TMT Overlabeling in Proteomic Samples by Methylamine, Molecular and Cellular Proteomics, 2025, 24, 100948

Le Bas, A.; Clarke, B. R.; Teelucksingh, T.; Lee, M.; El Omari, K.; Giltrap, A. M.; McMahon, S. A.; Liu, H.; Beale, J. H.; Mykhaylyk, V.; Duman, R.; Paterson, N. G.; Ward, P. H.; Harrison, P. J.; Weckener, M.; Pardon, E.; Steyaert, J.; Liu, H.; Quigley, A.; Davis, B. G.; Wagner, A.; Whitfield C. and Naismith, J. H. Structure of WzxE the Lipid III Flippase for Enterobacterial Common Antigen Polysaccharide. Open Biology, 2025, 15, 240310

Giltrap, A. M.µ; Morris, N.; Dong, Y. Y.; Cochrane, S. A.; Krulle, T.; Hoekman, S.; Semmelroth, M.; Wollnik, C.; Palmai-Pallag, T.; Carpenter, E. P.; Hollick, J.; Parkes, A.; Rudhard, Y. and Davis, B. G.µ; Lipid-Modulated, Graduated Inhibition of N-Glycosylation Pathway Priming Suggests Wide Tolerance of ER Proteostasis to Stress, ACS Central Science, 2025, 11, 107 (µ corresponding author)

Bedding, M. J.; Forster, B. C.; Giltrap, A. M.; Stevens, M. T.; Corcilius, L.; Britton, W. J. and Payne, R. J. Modular Total Synthesis And Antimycobacterial Activity of Rufomycins, Organic Letters, 2024, 26, 10993

Giltrap, A. M.*; Yuan, Y.*; and Davis, B. G. Late-Stage Functionalization of Living Organisms: Rethinking Selectivity in Biology, Chemical Reviews, 2024, 124, 889 [review]

Fu, X. P.; Yuan, Y.; Jha, A.; Levin, N.; Giltrap, A. M.; Ren, J.; Mamalis, D.; Mohammed, S.; and Davis, B. G. Stereoretentive Post-Translational Protein Editing, ACS Central Science, 2023, 9(3), 405

Dowman, L. J; Kulkarni, S. S.; Alegre-Requena, J. V.; Giltrap, A. M.; Norman, A. R.; Sharma, A.; Gallegos, L. C.; Mackay, A. S.; Welegedara, A. P.; Watson, E. E.; van Raad, D.; Niederacher, G.; Huhmann, S.; Proschogo, N.; Patel, K.; Larance, M.; Becker, C. F. W.; Mackay, J. P.; Lakhwani, G.; Huber, T.; Paton R. S. and Payne, R. J. Site-selective Photocatalytic Functionalization of Peptides and Proteins at Selenocysteine, Nature Communications, 2022, 13, 6885

Buchanan, C. J.; Gaunt, B.; Harrison, P. J.; Yang, Y.; Liu, J.; Khan, A.; Giltrap, A. M.; Le Bas, A.; Ward, P. N.; Gupta, K.; Dumoux, M.; Tan, T. L.; Daga, S.; Picchiotti, N.; Baldassarri, M.; Benetti, E.; Fallerini, C.; Fava, F.; Giliberti, A.; Koukos, P. I.; Davy, M. J.; Lakshminarayanan, A.; Xue, X.; Papadakis, G.; Deimel, L. P.; Casablancas-Antràs, V.; Claridge, T. D. W.; Bonvin, A. M. J. J.;  Sattentau, Q. J.; Furini, S.;  Gori, M.; Huo, J.; Owens, R. J.; Schaffitzel, C.; Berger, I.; Renieri, A.; GEN-COVID Multicenter Study, Naismith, J. H. Baldwin, A. J. and Davis B. G. Pathogen-sugar Interactions Revealed by Universal Saturation Transfer Analysis. Science 2022, 337, eabm3125.

Mollner, T. A.; Giltrap, A. M.; Zeng, Y.; Demyanenko, Y.; Buchanan, C.; Oehlrich, D.; Baldwin, A. J.; Anthony, D. C.; Mohammed, S. and Davis, B. G. Reductive Site-selective Atypical C,Z-type/N2-C2 cleavage allows C-terminal protein amidation. Science Advances 2022, 8, eabl8675.

Hawkins, P. M. E.; Tran W.; Nagalingam, G.; Cheung, C-Y.; Giltrap, A. M.; Cook, G. M.;  Britton, W. J. and Payne, R. J. Total Synthesis and Antimycobacterial Activity of Ohmyungsamycins A, Deoxyecumicin, and Ecumicin. Chemistry – A European Journal 2020, 26, 15200-15205.

Josephson, B.; Fehl, C.; Isenegger, P. G.; Nadal, S.; Wright, T. H.; Poh, A. W. J.; Bower, B. J.; Giltrap, A. M.; Chen, L.; Batchelor-McAuley, C.; Roper, G.; Arisa, O.; Sap, J. B. I.; Kawamura, A.; Baldwin, A. J.; Mohammed, S.; Compton, R. G.; Gouverneur, V. and Davis, B. G. Light-driven Posttranslational Installation of Reactive Protein Side Chains. Nature 2020, 585, 530-537.

Karas, J. A.; Chen, F.; Schneider-Futschik E. K.; Kang, Z.; Hussein, M.; Swarbrick, J.; Hoyer, D.; Giltrap, A. M.; Payne, R. J.; Li, J. and Velkov, T. Synthesis and Structure-activity Relationships of Teixobactin. Annals of the New York Academy of Sciences 2020, 1459, 86-105. [review]

Chiorean, S.; Antwi, I.; Carney, D. W.; Kotsogianni, I.; Giltrap, A. M.; Alexander, F. M.; Cochrane, S. A.; Payne, R. J.; Martin, N. I.; Henninot, A. and Vederas, J. C. Dissecting the Binding Interactions of Teixobactin with the Bacterial Cell-wall Precursor Lipid II. ChemBioChem 2019, 20, 1-5.

Stanley, C. P.; Maghzal, G. J.; Ayer, A.; Talib, J.; Giltrap, A. M.; Shengule, S.; Wolhuter, K.; Wang, Y.; Chadha, P.; Suarna, C.; Prysyazhna, O.; Scotcher, J.; Dunn, L. L.; Prado, F. M.; Nguyen, N.; Odiba, J. O.; Baell, J. B.; Stasch, J-P.; Yamamoto, Y.; Mascio, P. D.; Eaton, P.; Payne, R. J. and Stocker, R. Singlet Molecular Oxygen Regulates Vascular Tone and Blood Pressure in Inflammation. Nature 2019, 566, 548-552.

Giltrap, A. M.; Haeckl, F. P. J.; Kurita, K. L.; Linington, R. G.; Payne, R. J. Synthetic Studies Toward the Skyllamycins: Total Synthesis and Generation of Simplified Analogues. Journal of Organic Chemistry 2018, 83, 7250-7270.

Hawkins, P. E. M.; Giltrap, A. M.; Nagalingham, G.; Britton, W. J.; Payne, R. J. Total Synthesis of Ecumicin. Organic Letters 2018, 20, 1019-1022.

Giltrap, A. M.; Haeckl, F. P. J.; Kurita, K. L.; Linington, R. G.; Payne, R. J. Total Synthesis of Skyllamycins A-C. Chemistry – A European Journal 2017, 23, 15046-15049.

Tran, A. T.; Watson, E. E.; Pujari, V.; Conroy, T.; Dowman, L. J.; Giltrap, A. M.; Pang, A.; Wong, W. R.; Linington, R. G.; Mahapatra, S.; Saunders, J.; Charman, S. A.; West, N. P.; Bugg, T. D. H.; Tod, J.; Dowson, C. G.; Roper, D. I.; Crick, D. C.; Britton, W. J.; Payne, R. J. Sansanmycin Natural Product Analogues as Potent and Selective Anti-Mycobacterials that Inhibit Lipid I Biosynthesis. Nature Communications 2017, 8, Article No. 14414.

Giltrap, A. M.*; Dowman, L. J.*; Nagalingam, G.; Ochoa, J. L.; Linington, R. G.; Britton, W. J.; Payne, R. J. Total Synthesis of Teixobactin. Organic Letters 2016, 18, 2788-2791.

Malins, L. R.; Giltrap, A. M.; Dowman, L. J.; Payne, R. J. Synthesis of B-Thiol Phenylalanine for Applications in One-Pot Ligation-Desulfurisation Chemistry. Organic Letters 2015, 17, 2070-2073.

Giltrap, A. M.; Cergol, K. M.; Pang, A.; Britton, W. J.; Payne, R. J. Total Synthesis of Fellutamide B and Deoxy-Fellutamides B, C and D. Marine Drugs 2013, 11, 2382-2397.

Davis, M. R.; Singh, E. K.; Wahyudi, H.; Alexander, L. D.; Kunicki, J. B.; Nazarova, L. A.; Fairweather, K. A.; Giltrap, A. M.; Jolliffe, K. A.; McAlpine, S. R. Synthesis of Sansalvamide A Peptidomimetics: Triazole, Oxazole, Thiazole and Pseudoproline Containing Compounds. Tetrahedron 2012, 68, 1029-1051.